Activity

Filter

Cancel
Date Panel Item Activity
8 actions
Deafness_IsolatedAndComplex v1.290 COL4A3 Chirag Patel Mode of inheritance for gene: COL4A3 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Deafness_IsolatedAndComplex v1.289 COL4A3 Chirag Patel edited their review of gene: COL4A3: Added comment: ARAS - 50%-60% typically exhibit hearing loss
ADAS - hearing loss is usually a very late development; Changed mode of inheritance: BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Deafness_IsolatedAndComplex v1.288 COL4A3 Chirag Patel Deleted their comment
Deafness_IsolatedAndComplex v1.288 COL4A3 Chirag Patel Marked gene: COL4A3 as ready
Deafness_IsolatedAndComplex v1.288 COL4A3 Chirag Patel Gene: col4a3 has been classified as Green List (High Evidence).
Deafness_IsolatedAndComplex v1.288 COL4A3 Chirag Patel commented on gene: COL4A3
Deafness_IsolatedAndComplex v1.288 Chirag Patel Copied gene COL4A3 from panel Mendeliome
Deafness_IsolatedAndComplex v1.288 COL4A3 Chirag Patel gene: COL4A3 was added
gene: COL4A3 was added to Deafness_IsolatedAndComplex. Sources: Expert Review Green,Victorian Clinical Genetics Services
Mode of inheritance for gene: COL4A3 was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes for gene: COL4A3 were set to Alport syndrome 2, autosomal recessive, MIM# 203780; Alport syndrome 3, autosomal dominant, MIM# 104200