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Ataxia v2.123 CYP7B1 Sangavi Sivagnanasundram gene: CYP7B1 was added
gene: CYP7B1 was added to Ataxia. Sources: Literature
Mode of inheritance for gene: CYP7B1 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: CYP7B1 were set to 40782215; 29126212
Phenotypes for gene: CYP7B1 were set to hereditary spastic paraplegia 5A, MONDO:0010047
Review for gene: CYP7B1 was set to GREEN
Added comment: PMID 29126212 and 40782215 report multiple individuals with autosomal recessive hereditary spastic paraplegia type 5 (SPG5) characterised by progressive spastic gait and gait ataxia.
Sources: Literature