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| Motor Neurone Disease v1.43 | ERBB4 | Sangavi Sivagnanasundram edited their review of gene: ERBB4: Changed publications: 31432357, 32638105, 33414559, 35873773, 38291418; Changed phenotypes: amyotrophic lateral sclerosis type 19, MONDO:0014223 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v1.43 | ERBB4 |
Sangavi Sivagnanasundram changed review comment from: Update to GDA and publications GREEN association for ALS - 6 other unrelated individuals reported with ALS and heterozygous variants in ERBB4 (PMID: 31432357, 32638105, 33414559, 35873773, 38291418) RED for Hirschsprung - only one affected individual identified (PMID: 29483666) RED for idiopathic hypogonadotropic hypogonadism (IHH) - only one affected individual identified (PMID: 36123965); to: Update to GDA and publications GREEN association for ALS - 6 other unrelated individuals reported with ALS and heterozygous variants in ERBB4 (PMID: 31432357, 32638105, 33414559, 35873773, 38291418) |
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| Motor Neurone Disease v1.43 | Sangavi Sivagnanasundram Added reviews for gene ERBB4 from panel Mendeliome | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.177 | ERBB4 | Bryony Thompson Classified gene: ERBB4 as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.177 | ERBB4 | Bryony Thompson Added comment: Comment on list classification: Limited gene-disease validity assessment by ClinGen ALS spectrum disorder GCEP - 30/09/2021 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.177 | ERBB4 | Bryony Thompson Gene: erbb4 has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.17 | ERBB4 | Bryony Thompson Marked gene: ERBB4 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.17 | ERBB4 | Bryony Thompson Gene: erbb4 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.17 | ERBB4 | Bryony Thompson Classified gene: ERBB4 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.17 | ERBB4 | Bryony Thompson Gene: erbb4 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Motor Neurone Disease v0.16 | ERBB4 |
Bryony Thompson gene: ERBB4 was added gene: ERBB4 was added to Motor Neuron Disease. Sources: Expert list Mode of inheritance for gene: ERBB4 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: ERBB4 were set to 24119685; 28889094 Phenotypes for gene: ERBB4 were set to Amyotrophic lateral sclerosis 19 MIM#615515 Review for gene: ERBB4 was set to GREEN Added comment: At least 4 cases with ALS Sources: Expert list |
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