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| Autoinflammatory Disorders v3.5 | FGR | Zornitza Stark Marked gene: FGR as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.5 | FGR | Zornitza Stark Gene: fgr has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.5 | FGR | Zornitza Stark Phenotypes for gene: FGR were changed from autoinflammatory bone disease; infantile vasculitis to Inborn error of immunity, MONDO:0003778, FGR-related | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.4 | FGR | Zornitza Stark Classified gene: FGR as Amber List (moderate evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.4 | FGR | Zornitza Stark Gene: fgr has been classified as Amber List (Moderate Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.3 | FGR | Zornitza Stark reviewed gene: FGR: Rating: AMBER; Mode of pathogenicity: None; Publications: ; Phenotypes: Inborn error of immunity, MONDO:0003778, FGR-related; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Autoinflammatory Disorders v3.3 | FGR |
Peter McNaughton gene: FGR was added gene: FGR was added to Autoinflammatory Disorders. Sources: Literature Mode of inheritance for gene: FGR was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: FGR were set to PMID: 31138708; PMID: 41920357 Phenotypes for gene: FGR were set to autoinflammatory bone disease; infantile vasculitis Mode of pathogenicity for gene: FGR was set to Other Review for gene: FGR was set to GREEN Added comment: FGR variants reported in patients with CRMO and mouse model demonstrating inflammasome activation. 13 family members across 3 generations with vasculitis, pulmonary haemorrhage, CRMO Sources: Literature |
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