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| Infertility and Recurrent Pregnancy Loss v0.159 | GNRH1 | Zornitza Stark Marked gene: GNRH1 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Infertility and Recurrent Pregnancy Loss v0.159 | GNRH1 | Zornitza Stark Gene: gnrh1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Infertility and Recurrent Pregnancy Loss v0.159 | GNRH1 | Zornitza Stark Classified gene: GNRH1 as Green List (high evidence) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Infertility and Recurrent Pregnancy Loss v0.159 | GNRH1 | Zornitza Stark Gene: gnrh1 has been classified as Green List (High Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Infertility and Recurrent Pregnancy Loss v0.82 | GNRH1 |
Jasmine Chew gene: GNRH1 was added gene: GNRH1 was added to Infertility and Pregnancy Loss. Sources: Literature Mode of inheritance for gene: GNRH1 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: GNRH1 were set to 19535795; 19567835; 32134721; 31200363; 26595427; 34923491 Phenotypes for gene: GNRH1 were set to Hypogonadotropic hypogonadism 12 with or without anosmia, MIM# 614841 Review for gene: GNRH1 was set to GREEN Added comment: New paper: i) PMID: 34923491- Two male probands with reproductive phenotypes (but not sterile) in their Indian cohort carried two novel pathogenic biallelic GNRH1 variants (p.Glu24Leu, c.238-2A>G); also reviewed previously reported cases with GNRH1 variants suggests GNRH1 biallelic variants lead to severe reproductive phenotype, with low gonadotropin levels. Sources: Literature |
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