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Susceptibility to Viral Infections v1.12 ITGAL Zornitza Stark Marked gene: ITGAL as ready
Susceptibility to Viral Infections v1.12 ITGAL Zornitza Stark Gene: itgal has been classified as Green List (High Evidence).
Susceptibility to Viral Infections v1.12 ITGAL Zornitza Stark Classified gene: ITGAL as Green List (high evidence)
Susceptibility to Viral Infections v1.12 ITGAL Zornitza Stark Gene: itgal has been classified as Green List (High Evidence).
Susceptibility to Viral Infections v1.11 ITGAL Zornitza Stark gene: ITGAL was added
gene: ITGAL was added to Susceptibility to Viral Infections. Sources: Literature
Mode of inheritance for gene: ITGAL was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: ITGAL were set to 41758928
Phenotypes for gene: ITGAL were set to Epidermodysplasia verruciformis, susceptibility to, 6, MIM#621588
Review for gene: ITGAL was set to GREEN
Added comment: 6 individuals from 4 families, including 2 parent-child pairs reported with biallelic variants in this gene and susceptibility to HPV resulting in lifelong occurrence of disseminated flat warts. Some supportive functional data.

Three different homozygous variants identified, two LoF and one missense.
Sources: Literature