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Cardiomyopathy_Paediatric v1.73 MT-ND6 Lucy Spencer Classified gene: MT-ND6 as Amber List (moderate evidence)
Cardiomyopathy_Paediatric v1.73 MT-ND6 Lucy Spencer Gene: mt-nd6 has been classified as Amber List (Moderate Evidence).
Cardiomyopathy_Paediatric v1.72 MT-ND6 Lucy Spencer gene: MT-ND6 was added
gene: MT-ND6 was added to Cardiomyopathy_Paediatric. Sources: Literature
Mode of inheritance for gene gene: MT-ND6 was set to MITOCHONDRIAL
Publications for gene: MT-ND6 were set to 34933128
Phenotypes for gene: MT-ND6 were set to Mitochondrial disease (MONDO:0044970), MT-ND6-related
Review for gene: MT-ND6 was set to AMBER
Added comment: PMID 34933128 reports 4 new patients and reviews the literature for individuals with Leigh syndrome and m.14453G>A in MT-ND6. 2 of the individuals were noted to have childhood/infantile onset HCM.
Sources: Literature