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Pituitary hormone deficiency v0.226 NLGN3 Chirag Patel reviewed gene: NLGN3: Rating: AMBER; Mode of pathogenicity: None; Publications: 36810932; Phenotypes: Hypogonadotropic hypogonadism MONDO:0018555; Mode of inheritance: X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Pituitary hormone deficiency v0.226 NLGN3 Chirag Patel Marked gene: NLGN3 as ready
Pituitary hormone deficiency v0.226 NLGN3 Chirag Patel Gene: nlgn3 has been classified as Amber List (Moderate Evidence).
Pituitary hormone deficiency v0.226 NLGN3 Chirag Patel Phenotypes for gene: NLGN3 were changed from X-linked complex neurodevelopmental disorder MONDO:0100148; {Autism susceptibility, X-linked 1} - MIM#300425 to X-linked complex neurodevelopmental disorder MONDO:0100148; {Autism susceptibility, X-linked 1} - MIM#300425; hypogonadotropic hypogonadism MONDO:0018555
Pituitary hormone deficiency v0.225 NLGN3 Chirag Patel Classified gene: NLGN3 as Amber List (moderate evidence)
Pituitary hormone deficiency v0.225 NLGN3 Chirag Patel Gene: nlgn3 has been classified as Amber List (Moderate Evidence).
Pituitary hormone deficiency v0.224 Chirag Patel Copied gene NLGN3 from panel Mendeliome
Pituitary hormone deficiency v0.224 NLGN3 Chirag Patel gene: NLGN3 was added
gene: NLGN3 was added to Pituitary hormone deficiency. Sources: Expert Review Green,Victorian Clinical Genetics Services
Mode of inheritance for gene: NLGN3 was set to X-LINKED: hemizygous mutation in males, biallelic mutations in females
Publications for gene: NLGN3 were set to 28584888; 12669065; 25167861
Phenotypes for gene: NLGN3 were set to X-linked complex neurodevelopmental disorder MONDO:0100148; {Autism susceptibility, X-linked 1} - MIM#300425