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Genetic Epilepsy v2.11 NRXN1 Sarah Milton Source Victorian Clinical Genetics Services was removed from NRXN1.
Source Australian Genomics Health Alliance Epilepsy Flagship was removed from NRXN1.
Mode of inheritance for gene NRXN1 was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal
Phenotypes for gene: NRXN1 were changed from Pitt-Hopkins-like syndrome 2 - MIM#614325 to Pitt-Hopkins-like syndrome 2 - MIM#614325; Complex neurodevelopmental disorder, MONDO:0100038, NRXN1-related
Genetic Epilepsy v2.10 Sarah Milton Added reviews for gene NRXN1 from panel Mendeliome
Genetic Epilepsy v2.0 NRXN1 Gene migrated from ENSG00000179915 to ENSG00000179915 (gene set migration)
Genetic Epilepsy v0.1525 NRXN1 Zornitza Stark Phenotypes for gene: NRXN1 were changed from Pitt-Hopkins-like syndrome 2 - MIM#614325 to Pitt-Hopkins-like syndrome 2 - MIM#614325
Genetic Epilepsy v0.1525 NRXN1 Zornitza Stark Marked gene: NRXN1 as ready
Genetic Epilepsy v0.1525 NRXN1 Zornitza Stark Gene: nrxn1 has been classified as Green List (High Evidence).
Genetic Epilepsy v0.1525 NRXN1 Zornitza Stark Phenotypes for gene: NRXN1 were changed from to Pitt-Hopkins-like syndrome 2 - MIM#614325
Genetic Epilepsy v0.1524 NRXN1 Zornitza Stark Publications for gene: NRXN1 were set to
Genetic Epilepsy v0.1523 NRXN1 Zornitza Stark Mode of inheritance for gene: NRXN1 was changed from BIALLELIC, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal
Genetic Epilepsy v0.1522 NRXN1 Zornitza Stark Mode of inheritance for gene: NRXN1 was changed from Unknown to BIALLELIC, autosomal or pseudoautosomal
Genetic Epilepsy v0.1514 NRXN1 Krithika Murali reviewed gene: NRXN1: Rating: GREEN; Mode of pathogenicity: None; Publications: 25486015, 19896112, 21964664, 30873608, 35101781, 22337556, 22670139; Phenotypes: Pitt-Hopkins-like syndrome 2 - MIM#614325; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Genetic Epilepsy v0.0 NRXN1 Zornitza Stark gene: NRXN1 was added
gene: NRXN1 was added to Genetic Epilepsy_AustralianGenomics_VCGS. Sources: Australian Genomics Health Alliance Epilepsy Flagship,Expert Review Green,Victorian Clinical Genetics Services
Mode of inheritance for gene: NRXN1 was set to Unknown