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Congenital hypothyroidism v0.104 NSD1 Chirag Patel Marked gene: NSD1 as ready
Congenital hypothyroidism v0.104 NSD1 Chirag Patel Gene: nsd1 has been classified as Amber List (Moderate Evidence).
Congenital hypothyroidism v0.104 NSD1 Chirag Patel Classified gene: NSD1 as Amber List (moderate evidence)
Congenital hypothyroidism v0.104 NSD1 Chirag Patel Gene: nsd1 has been classified as Amber List (Moderate Evidence).
Congenital hypothyroidism v0.103 NSD1 Chirag Patel gene: NSD1 was added
gene: NSD1 was added to Congenital hypothyroidism. Sources: Literature
Mode of inheritance for gene: NSD1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Publications for gene: NSD1 were set to 41024235; 34350334; 15942875
Phenotypes for gene: NSD1 were set to Sotos syndrome, MONDO:0019349
Review for gene: NSD1 was set to AMBER
Added comment: 3 individuals with Sotos syndrome and heterozygous loss‑of‑function NSD1 variants, with permanent congenital hypothyroidism. Congenital hypothyroidism in Sotos syndrome may be an underreported feature.
Sources: Literature