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Bone Marrow Failure v1.118 OSM Bryony Thompson Marked gene: OSM as ready
Bone Marrow Failure v1.118 OSM Bryony Thompson Gene: osm has been classified as Green List (High Evidence).
Bone Marrow Failure v1.118 OSM Bryony Thompson Classified gene: OSM as Green List (high evidence)
Bone Marrow Failure v1.118 OSM Bryony Thompson Gene: osm has been classified as Green List (High Evidence).
Bone Marrow Failure v1.117 OSM Bryony Thompson gene: OSM was added
gene: OSM was added to Bone Marrow Failure. Sources: Literature
Mode of inheritance for gene: OSM was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: OSM were set to 39847438; 40309776; 17118758
Phenotypes for gene: OSM were set to bone marrow failure syndrome MONDO:0000159
Review for gene: OSM was set to GREEN
Added comment: 6 individuals with with OSM deficiency and an inherited severe bone marrow failure syndrome from 3 consanguineous families with 2 different homozygous LoF variants. Supporting zebrafish and mouse models.
Sources: Literature