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Colorectal Cancer and Polyposis v0.40 POLE Zornitza Stark Marked gene: POLE as ready
Colorectal Cancer and Polyposis v0.40 POLE Zornitza Stark Gene: pole has been classified as Green List (High Evidence).
Colorectal Cancer and Polyposis v0.13 POLE Chirag Patel Classified gene: POLE as Green List (high evidence)
Colorectal Cancer and Polyposis v0.13 POLE Chirag Patel Gene: pole has been classified as Green List (High Evidence).
Colorectal Cancer and Polyposis v0.10 POLE Chirag Patel edited their review of gene: POLE: Changed phenotypes: Colorectal cancer, MONDO:0005575, Polyposis, MONDO:0000147, POLE-related polyposis and colorectal cancer syndrome, MONDO:0100287, POLE-associated polyposis, MIM#615083
Colorectal Cancer and Polyposis v0.6 POLE Chirag Patel gene: POLE was added
gene: POLE was added to Colorectal Cancer and Polyposis. Sources: Expert list,Expert Review
Mode of inheritance for gene: POLE was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes for gene: POLE were set to POLE-related polyposis and colorectal cancer syndrome, MONDO:0100287; POLE-associated polyposis, MIM#615083
Review for gene: POLE was set to GREEN
Added comment: ClinGen definitive. Colorectal cancers and/or polyposis reported in condition. GOF variants.
Sources: Expert list, Expert Review