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Genetic Epilepsy v2.9 SOX10 Lucy Spencer Classified gene: SOX10 as Green List (high evidence)
Genetic Epilepsy v2.9 SOX10 Lucy Spencer Gene: sox10 has been classified as Green List (High Evidence).
Genetic Epilepsy v2.8 SOX10 Lucy Spencer gene: SOX10 was added
gene: SOX10 was added to Genetic Epilepsy. Sources: Literature
Mode of inheritance for gene: SOX10 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: SOX10 were set to 29792164; 35725288
Phenotypes for gene: SOX10 were set to PCWH syndrome MIM#609136
Review for gene: SOX10 was set to GREEN
Added comment: Seizures are a rare feature of this disorder and may be caused by the delayed myelination/demyelination associated with this gene. There are several reports in the literature of individuals with seizures as part of PCWH syndrome (PMIDs: 29792164, 35725288).
Sources: Literature