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Genomic screening in children: BabyScreen+ v0.58 SPTLC1 Lilian Rudd gene: SPTLC1 was added
gene: SPTLC1 was added to Genomic screening in children: BabyScreen+. Sources: Expert list
Mode of inheritance for gene: SPTLC1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: SPTLC1 were set to PMID: 34059824
Phenotypes for gene: SPTLC1 were set to Amyotrophic lateral sclerosis 27, juvenile MIM#620285
Review for gene: SPTLC1 was set to GREEN
Added comment: Specific variants (exon 2) cause the childhood onset.
Treatment serine
Non-genetic confirmatory test: Sphingolipid levels
Sources: Expert list