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Callosome v0.568 TAF2 Zornitza Stark Marked gene: TAF2 as ready
Callosome v0.568 TAF2 Zornitza Stark Gene: taf2 has been classified as Green List (High Evidence).
Callosome v0.568 TAF2 Zornitza Stark Phenotypes for gene: TAF2 were changed from Intellectual disability, autosomal recessive 40, MIM# 615599 to Intellectual development disorder, autosomal recessive 40, MIM# 615599
Callosome v0.567 TAF2 Zornitza Stark Phenotypes for gene: TAF2 were changed from intellectual disability; epilepsy; thin corpus callosum to Intellectual disability, autosomal recessive 40, MIM# 615599
Callosome v0.566 TAF2 Zornitza Stark Classified gene: TAF2 as Green List (high evidence)
Callosome v0.566 TAF2 Zornitza Stark Gene: taf2 has been classified as Green List (High Evidence).
Callosome v0.565 TAF2 Boris Keren gene: TAF2 was added
gene: TAF2 was added to Callosome. Sources: Literature
Mode of inheritance for gene: TAF2 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: TAF2 were set to PMID: 34474177
Phenotypes for gene: TAF2 were set to intellectual disability; epilepsy; thin corpus callosum
Penetrance for gene: TAF2 were set to Complete
Mode of pathogenicity for gene: TAF2 was set to Other
Review for gene: TAF2 was set to GREEN
gene: TAF2 was marked as current diagnostic
Added comment: Most patients have severe intellectual disability, microcephaly, thin corpus callosum. 9 reported patients from 4 families.
Only missenses are reported for now but the mechanism is currently unknown
Sources: Literature