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| Defects of intrinsic and innate immunity v0.179 | TLR4 | Bryony Thompson Marked gene: TLR4 as ready | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v0.179 | TLR4 | Bryony Thompson Gene: tlr4 has been classified as Red List (Low Evidence). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Defects of intrinsic and innate immunity v0.179 | TLR4 |
Bryony Thompson gene: TLR4 was added gene: TLR4 was added to Defects of innate immunity. Sources: Expert list Mode of inheritance for gene: TLR4 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: TLR4 were set to 32042729; 31442584 Phenotypes for gene: TLR4 were set to Inflammatory bowel disease MONDO:0005265 Review for gene: TLR4 was set to RED Added comment: The IUIS IEI committee has this gene listed as a cause of inflammatory bowel disease under the TLR Signaling Pathway Deficiency categorisation, but I cannot find any reports of Mendelian disease. There are knockout mouse models with ulcerative colitis. Sources: Expert list |
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