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Cardiomyopathy_Paediatric v1.21 TRMT5 Zornitza Stark Marked gene: TRMT5 as ready
Cardiomyopathy_Paediatric v1.21 TRMT5 Zornitza Stark Gene: trmt5 has been classified as Amber List (Moderate Evidence).
Cardiomyopathy_Paediatric v1.21 TRMT5 Zornitza Stark Classified gene: TRMT5 as Amber List (moderate evidence)
Cardiomyopathy_Paediatric v1.21 TRMT5 Zornitza Stark Gene: trmt5 has been classified as Amber List (Moderate Evidence).
Cardiomyopathy_Paediatric v1.20 TRMT5 Zornitza Stark gene: TRMT5 was added
gene: TRMT5 was added to Cardiomyopathy_Paediatric. Sources: Literature
Mode of inheritance for gene: TRMT5 was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: TRMT5 were set to 26189817
Phenotypes for gene: TRMT5 were set to combined oxidative phosphorylation defect type 26, MONDO:0014684
Review for gene: TRMT5 was set to AMBER
Added comment: PMID 26189817 reports 2 individuals from 2 families with biallelic TRMT5 variants presenting with childhood‑onset hypertrophic cardiomyopathy and multisystemic mitochondrial disease.
Sources: Literature