Activity

Filter

Panel

Version

Gene or Genomic Entity Name

Date from

Date to

User type

Training users only

Event Types (select to filter, or leave blank for all)

Gene/Entity Additions

Rating/Classification Changes

Flagged genes only

Cancel

Date	Panel	Item	Activity
Filter activities 14 actions
07 Jun 2026	Hereditary Spastic Paraplegia v2.0	VAMP1	Gene migrated from ENSG00000139190 to ENSG00000139190 (gene set migration)
20 Sep 2020	Hereditary Spastic Paraplegia v0.148	VAMP1	Zornitza Stark changed review comment from: Spasticity is a prominent feature of this condition. Single founder variant in multiple families from Newfoundland. Sources: Expert list; to: Spasticity is a prominent feature of this condition. Single founder variant in multiple families from Newfoundland. Bi-allelic variants cause a myasthenic syndrome. Sources: Expert list
20 Sep 2020	Hereditary Spastic Paraplegia v0.148	VAMP1	Zornitza Stark Publications for gene: VAMP1 were set to
20 Sep 2020	Hereditary Spastic Paraplegia v0.147	VAMP1	Zornitza Stark Classified gene: VAMP1 as Amber List (moderate evidence)
20 Sep 2020	Hereditary Spastic Paraplegia v0.147	VAMP1	Zornitza Stark Gene: vamp1 has been classified as Amber List (Moderate Evidence).
20 Sep 2020	Hereditary Spastic Paraplegia v0.146	VAMP1	Zornitza Stark Tag founder tag was added to gene: VAMP1.
20 Sep 2020	Hereditary Spastic Paraplegia v0.146	VAMP1	Zornitza Stark changed review comment from: Spasticity is a prominent feature of this condition. Sources: Expert list; to: Spasticity is a prominent feature of this condition. Single founder variant in multiple families from Newfoundland. Sources: Expert list
20 Sep 2020	Hereditary Spastic Paraplegia v0.146	VAMP1	Zornitza Stark edited their review of gene: VAMP1: Changed rating: AMBER
20 Sep 2020	Hereditary Spastic Paraplegia v0.146	VAMP1	Zornitza Stark edited their review of gene: VAMP1: Changed publications: 22958904; Changed phenotypes: Spastic ataxia 1, autosomal dominant, MIM# 108600
18 Apr 2020	Hereditary Spastic Paraplegia v0.57	VAMP1	Zornitza Stark Marked gene: VAMP1 as ready
18 Apr 2020	Hereditary Spastic Paraplegia v0.57	VAMP1	Zornitza Stark Gene: vamp1 has been classified as Green List (High Evidence).
18 Apr 2020	Hereditary Spastic Paraplegia v0.57	VAMP1	Zornitza Stark Classified gene: VAMP1 as Green List (high evidence)
18 Apr 2020	Hereditary Spastic Paraplegia v0.57	VAMP1	Zornitza Stark Gene: vamp1 has been classified as Green List (High Evidence).
18 Apr 2020	Hereditary Spastic Paraplegia v0.56	VAMP1	Zornitza Stark gene: VAMP1 was added gene: VAMP1 was added to Hereditary Spastic Paraplegia - paediatric. Sources: Expert list Mode of inheritance for gene: VAMP1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: VAMP1 were set to Spastic ataxia 1, autosomal dominant, MIM# 108600 Review for gene: VAMP1 was set to GREEN Added comment: Spasticity is a prominent feature of this condition. Sources: Expert list