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Autonomic neuropathy v2.0 ATL3 Gene migrated from ENSG00000184743 to ENSG00000184743 (gene set migration)
Autonomic neuropathy v2.0 RETREG1 Gene migrated from ENSG00000154153 to ENSG00000154153 (gene set migration)
Autonomic neuropathy v2.0 LIFR Gene migrated from ENSG00000113594 to ENSG00000113594 (gene set migration)
Autonomic neuropathy v2.0 DBH Gene migrated from ENSG00000123454 to ENSG00000123454 (gene set migration)
Autonomic neuropathy v2.0 LMNB1 Gene migrated from ENSG00000113368 to ENSG00000113368 (gene set migration)
Autonomic neuropathy v2.0 MADD Gene migrated from ENSG00000110514 to ENSG00000110514 (gene set migration)
Autonomic neuropathy v2.0 PHOX2B Gene migrated from ENSG00000109132 to ENSG00000109132 (gene set migration)
Autonomic neuropathy v2.0 SCN9A Gene migrated from ENSG00000169432 to ENSG00000169432 (gene set migration)
Autonomic neuropathy v2.0 GMPPA Gene migrated from ENSG00000144591 to ENSG00000144591 (gene set migration)
Autonomic neuropathy v2.0 AAAS Gene migrated from ENSG00000094914 to ENSG00000094914 (gene set migration)
Autonomic neuropathy v2.0 WNK1 Gene migrated from ENSG00000060237 to ENSG00000060237 (gene set migration)
Autonomic neuropathy v2.0 ELP1 Gene migrated from ENSG00000070061 to ENSG00000070061 (gene set migration)
Autonomic neuropathy v2.0 SPTLC2 Gene migrated from ENSG00000100596 to ENSG00000100596 (gene set migration)
Autonomic neuropathy v2.0 SPTLC1 Gene migrated from ENSG00000090054 to ENSG00000090054 (gene set migration)
Autonomic neuropathy v2.0 SCN11A Gene migrated from ENSG00000168356 to ENSG00000168356 (gene set migration)
Autonomic neuropathy v2.0 NTRK1 Gene migrated from ENSG00000198400 to ENSG00000198400 (gene set migration)
Autonomic neuropathy v2.0 PRDM12 Gene migrated from ENSG00000130711 to ENSG00000130711 (gene set migration)
Autonomic neuropathy v2.0 NGF Gene migrated from ENSG00000134259 to ENSG00000134259 (gene set migration)
Autonomic neuropathy v2.0 DST Gene migrated from ENSG00000151914 to ENSG00000151914 (gene set migration)
Autonomic neuropathy v2.0 Panel migrated to gene set Ensemblv115. Source version: v1.2
Autonomic neuropathy v1.2 Zornitza Stark HPO terms changed from Abnormality of the autonomic nervous system HP:0002270 to
List of related panels changed from to Abnormality of the autonomic nervous system HP:0002270
Autonomic neuropathy v1.1 Zornitza Stark HPO terms changed from to Abnormality of the autonomic nervous system HP:0002270
Autonomic neuropathy v1.0 Zornitza Stark promoted panel to version 1.0
Autonomic neuropathy v0.51 NGF Zornitza Stark Marked gene: NGF as ready
Autonomic neuropathy v0.51 NGF Zornitza Stark Gene: ngf has been classified as Green List (High Evidence).
Autonomic neuropathy v0.51 GMPPA Ain Roesley Phenotypes for gene: GMPPA were changed from # 615510 ALACRIMA, ACHALASIA, AND MENTAL RETARDATION SYNDROME; AAMR to Alacrima, achalasia, and impaired intellectual development syndrome (MIM# 615510)
Autonomic neuropathy v0.50 DST Zornitza Stark Publications for gene: DST were set to
Autonomic neuropathy v0.49 DST Zornitza Stark Classified gene: DST as Green List (high evidence)
Autonomic neuropathy v0.49 DST Zornitza Stark Gene: dst has been classified as Green List (High Evidence).
Autonomic neuropathy v0.48 DST Alison Yeung edited their review of gene: DST: Added comment: Since first family published in 2012, there have been two other families published. This is a green gene in the hereditary neuropathy panel.; Changed rating: GREEN; Changed publications: 30371979, 28468842
Autonomic neuropathy v0.48 RETREG1 Zornitza Stark Phenotypes for gene: RETREG1 were changed from OMIM# 613115 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIB; HSAN2B to Neuropathy, hereditary sensory and autonomic, type IIB, MIM# 613115; MONDO:0013142
Autonomic neuropathy v0.47 RETREG1 Zornitza Stark Publications for gene: RETREG1 were set to
Autonomic neuropathy v0.46 RETREG1 Zornitza Stark reviewed gene: RETREG1: Rating: GREEN; Mode of pathogenicity: None; Publications: 19838196, 24327336, 31737055, 31596031; Phenotypes: Neuropathy, hereditary sensory and autonomic, type IIB, MIM# 613115, MONDO:0013142; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Autonomic neuropathy v0.46 PRDM12 Zornitza Stark Phenotypes for gene: PRDM12 were changed from OMIM# 616488 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VIII; HSAN8 to Neuropathy, hereditary sensory and autonomic, type VIII, MIM# 616488; MONDO:0014662
Autonomic neuropathy v0.45 PRDM12 Zornitza Stark Publications for gene: PRDM12 were set to
Autonomic neuropathy v0.44 PRDM12 Zornitza Stark reviewed gene: PRDM12: Rating: GREEN; Mode of pathogenicity: None; Publications: 26005867, 33789102, 33010785, 32828702; Phenotypes: Neuropathy, hereditary sensory and autonomic, type VIII, MIM# 616488, MONDO:0014662; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Autonomic neuropathy v0.44 ELP1 Zornitza Stark Phenotypes for gene: ELP1 were changed from OMIM# 223900 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE III; HSAN3 to Dysautonomia, familial, MIM# 223900; Riley-Day syndrome MONDO:0009131
Autonomic neuropathy v0.43 ELP1 Zornitza Stark Publications for gene: ELP1 were set to
Autonomic neuropathy v0.42 ELP1 Zornitza Stark reviewed gene: ELP1: Rating: GREEN; Mode of pathogenicity: None; Publications: 11179008, 11179021, 17644305; Phenotypes: Dysautonomia, familial, MIM# 223900, Riley-Day syndrome MONDO:0009131; Mode of inheritance: BIALLELIC, autosomal or pseudoautosomal
Autonomic neuropathy v0.42 LMNB1 Zornitza Stark Tag SV/CNV tag was added to gene: LMNB1.
Autonomic neuropathy v0.42 LIFR Alison Yeung Marked gene: LIFR as ready
Autonomic neuropathy v0.42 LIFR Alison Yeung Gene: lifr has been classified as Green List (High Evidence).
Autonomic neuropathy v0.42 LIFR Alison Yeung Classified gene: LIFR as Green List (high evidence)
Autonomic neuropathy v0.42 LIFR Alison Yeung Gene: lifr has been classified as Green List (High Evidence).
Autonomic neuropathy v0.41 LIFR Alison Yeung gene: LIFR was added
gene: LIFR was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: LIFR was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: LIFR were set to OMIM# 601559 STUVE-WIEDEMANN SYNDROME; STWS
gene: LIFR was marked as current diagnostic
Added comment: Dysautonomia a common feature
Sources: Literature
Autonomic neuropathy v0.39 DBH Alison Yeung Marked gene: DBH as ready
Autonomic neuropathy v0.39 DBH Alison Yeung Gene: dbh has been classified as Green List (High Evidence).
Autonomic neuropathy v0.39 DBH Alison Yeung Classified gene: DBH as Green List (high evidence)
Autonomic neuropathy v0.39 DBH Alison Yeung Gene: dbh has been classified as Green List (High Evidence).
Autonomic neuropathy v0.38 DBH Alison Yeung gene: DBH was added
gene: DBH was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: DBH was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: DBH were set to 21209083; 11857564
Phenotypes for gene: DBH were set to OMIM# 223360 ORTHOSTATIC HYPOTENSION 1; ORTHYP1
Review for gene: DBH was set to GREEN
Added comment: Two unrelated families reported and functional studies
Sources: Literature
Autonomic neuropathy v0.37 LMNB1 Alison Yeung Marked gene: LMNB1 as ready
Autonomic neuropathy v0.37 LMNB1 Alison Yeung Gene: lmnb1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.37 LMNB1 Alison Yeung Classified gene: LMNB1 as Green List (high evidence)
Autonomic neuropathy v0.37 LMNB1 Alison Yeung Gene: lmnb1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.36 LMNB1 Alison Yeung gene: LMNB1 was added
gene: LMNB1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: LMNB1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: LMNB1 were set to OMIM# 169500 LEUKODYSTROPHY, DEMYELINATING, ADULT-ONSET, AUTOSOMAL DOMINANT; ADLD
Review for gene: LMNB1 was set to GREEN
gene: LMNB1 was marked as current diagnostic
Added comment: Autonomic dysfunction a common feature
Sources: Literature
Autonomic neuropathy v0.35 MADD Alison Yeung Marked gene: MADD as ready
Autonomic neuropathy v0.35 MADD Alison Yeung Gene: madd has been classified as Green List (High Evidence).
Autonomic neuropathy v0.35 MADD Alison Yeung Classified gene: MADD as Green List (high evidence)
Autonomic neuropathy v0.35 MADD Alison Yeung Gene: madd has been classified as Green List (High Evidence).
Autonomic neuropathy v0.34 MADD Alison Yeung gene: MADD was added
gene: MADD was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: MADD was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: MADD were set to OMIM# 619004 DEEAH SYNDROME; DEEAH
Review for gene: MADD was set to GREEN
gene: MADD was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.33 PHOX2B Alison Yeung Marked gene: PHOX2B as ready
Autonomic neuropathy v0.33 PHOX2B Alison Yeung Gene: phox2b has been classified as Green List (High Evidence).
Autonomic neuropathy v0.33 PHOX2B Alison Yeung Classified gene: PHOX2B as Green List (high evidence)
Autonomic neuropathy v0.33 PHOX2B Alison Yeung Gene: phox2b has been classified as Green List (High Evidence).
Autonomic neuropathy v0.32 PHOX2B Alison Yeung gene: PHOX2B was added
gene: PHOX2B was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: PHOX2B was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: PHOX2B were set to OMIM# 209880 CENTRAL HYPOVENTILATION SYNDROME, CONGENITAL; CCHS
Review for gene: PHOX2B was set to GREEN
gene: PHOX2B was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.31 SCN9A Alison Yeung Marked gene: SCN9A as ready
Autonomic neuropathy v0.31 SCN9A Alison Yeung Gene: scn9a has been classified as Green List (High Evidence).
Autonomic neuropathy v0.31 SCN9A Alison Yeung Classified gene: SCN9A as Green List (high evidence)
Autonomic neuropathy v0.31 SCN9A Alison Yeung Gene: scn9a has been classified as Green List (High Evidence).
Autonomic neuropathy v0.30 SCN9A Alison Yeung gene: SCN9A was added
gene: SCN9A was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: SCN9A was set to BIALLELIC, autosomal or pseudoautosomal
Publications for gene: SCN9A were set to 23596073
Phenotypes for gene: SCN9A were set to OMIM# 243000 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IID, INCLUDED; HSAN2D,
Review for gene: SCN9A was set to GREEN
Added comment: Two unrelated Japanese families reported
Sources: Literature
Autonomic neuropathy v0.29 GMPPA Alison Yeung Marked gene: GMPPA as ready
Autonomic neuropathy v0.29 GMPPA Alison Yeung Gene: gmppa has been classified as Green List (High Evidence).
Autonomic neuropathy v0.29 GMPPA Alison Yeung Classified gene: GMPPA as Green List (high evidence)
Autonomic neuropathy v0.29 GMPPA Alison Yeung Gene: gmppa has been classified as Green List (High Evidence).
Autonomic neuropathy v0.28 GMPPA Alison Yeung gene: GMPPA was added
gene: GMPPA was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: GMPPA was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: GMPPA were set to # 615510 ALACRIMA, ACHALASIA, AND MENTAL RETARDATION SYNDROME; AAMR
Review for gene: GMPPA was set to GREEN
gene: GMPPA was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.27 AAAS Alison Yeung Marked gene: AAAS as ready
Autonomic neuropathy v0.27 AAAS Alison Yeung Gene: aaas has been classified as Green List (High Evidence).
Autonomic neuropathy v0.27 AAAS Alison Yeung Classified gene: AAAS as Green List (high evidence)
Autonomic neuropathy v0.27 AAAS Alison Yeung Gene: aaas has been classified as Green List (High Evidence).
Autonomic neuropathy v0.26 AAAS Alison Yeung gene: AAAS was added
gene: AAAS was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: AAAS was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: AAAS were set to OMIM# 231550 ACHALASIA-ADDISONIANISM-ALACRIMA SYNDROME; AAAS
Review for gene: AAAS was set to GREEN
gene: AAAS was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.25 WNK1 Alison Yeung Marked gene: WNK1 as ready
Autonomic neuropathy v0.25 WNK1 Alison Yeung Gene: wnk1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.25 WNK1 Alison Yeung Classified gene: WNK1 as Green List (high evidence)
Autonomic neuropathy v0.25 WNK1 Alison Yeung Gene: wnk1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.24 WNK1 Alison Yeung gene: WNK1 was added
gene: WNK1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: WNK1 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: WNK1 were set to # 201300 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA; HSAN2A
Review for gene: WNK1 was set to GREEN
gene: WNK1 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.23 ATL3 Alison Yeung Phenotypes for gene: ATL3 were changed from OMIM# 201300 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA; HSAN2A to # 615632 NEUROPATHY, HEREDITARY SENSORY, TYPE IF; HSN1F
Autonomic neuropathy v0.22 ATL3 Alison Yeung Classified gene: ATL3 as Red List (low evidence)
Autonomic neuropathy v0.22 ATL3 Alison Yeung Gene: atl3 has been classified as Red List (Low Evidence).
Autonomic neuropathy v0.21 ATL3 Alison Yeung commented on gene: ATL3: Incorrect OMIM phenotype entered in previous review. ATL3 variants not associated with autonomic dysfunction.
Autonomic neuropathy v0.21 ATL3 Alison Yeung reviewed gene: ATL3: Rating: RED; Mode of pathogenicity: None; Publications: ; Phenotypes: # 615632 NEUROPATHY, HEREDITARY SENSORY, TYPE IF, HSN1F; Mode of inheritance: MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown; Current diagnostic: yes
Autonomic neuropathy v0.21 ATL3 Alison Yeung Deleted their review
Autonomic neuropathy v0.21 SPTLC2 Alison Yeung Marked gene: SPTLC2 as ready
Autonomic neuropathy v0.21 SPTLC2 Alison Yeung Gene: sptlc2 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.21 SPTLC2 Alison Yeung Classified gene: SPTLC2 as Green List (high evidence)
Autonomic neuropathy v0.21 SPTLC2 Alison Yeung Gene: sptlc2 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.20 SPTLC2 Alison Yeung gene: SPTLC2 was added
gene: SPTLC2 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: SPTLC2 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: SPTLC2 were set to OMIM# 613640 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IC; HSAN1C
Review for gene: SPTLC2 was set to GREEN
gene: SPTLC2 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.19 ATL3 Alison Yeung Marked gene: ATL3 as ready
Autonomic neuropathy v0.19 ATL3 Alison Yeung Gene: atl3 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.19 ATL3 Alison Yeung Classified gene: ATL3 as Green List (high evidence)
Autonomic neuropathy v0.19 ATL3 Alison Yeung Gene: atl3 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.18 ATL3 Alison Yeung gene: ATL3 was added
gene: ATL3 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: ATL3 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: ATL3 were set to OMIM# 201300 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIA; HSAN2A
Review for gene: ATL3 was set to GREEN
gene: ATL3 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.17 PRDM12 Alison Yeung Marked gene: PRDM12 as ready
Autonomic neuropathy v0.17 PRDM12 Alison Yeung Gene: prdm12 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.17 PRDM12 Alison Yeung Classified gene: PRDM12 as Green List (high evidence)
Autonomic neuropathy v0.17 PRDM12 Alison Yeung Gene: prdm12 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.16 PRDM12 Alison Yeung gene: PRDM12 was added
gene: PRDM12 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: PRDM12 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: PRDM12 were set to OMIM# 616488 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VIII; HSAN8
Review for gene: PRDM12 was set to GREEN
gene: PRDM12 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.15 ELP1 Alison Yeung Classified gene: ELP1 as Green List (high evidence)
Autonomic neuropathy v0.15 ELP1 Alison Yeung Gene: elp1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.14 ELP1 Alison Yeung Marked gene: ELP1 as ready
Autonomic neuropathy v0.14 ELP1 Alison Yeung Gene: elp1 has been classified as Red List (Low Evidence).
Autonomic neuropathy v0.14 ELP1 Alison Yeung gene: ELP1 was added
gene: ELP1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: ELP1 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: ELP1 were set to OMIM# 223900 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE III; HSAN3
Review for gene: ELP1 was set to GREEN
gene: ELP1 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.13 SPTLC1 Alison Yeung Marked gene: SPTLC1 as ready
Autonomic neuropathy v0.13 SPTLC1 Alison Yeung Gene: sptlc1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.13 SPTLC1 Alison Yeung Classified gene: SPTLC1 as Green List (high evidence)
Autonomic neuropathy v0.13 SPTLC1 Alison Yeung Gene: sptlc1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.12 SPTLC1 Alison Yeung gene: SPTLC1 was added
gene: SPTLC1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: SPTLC1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: SPTLC1 were set to OMIM# 162400 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IA; HSAN1A
Review for gene: SPTLC1 was set to GREEN
gene: SPTLC1 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.11 DST Alison Yeung Marked gene: DST as ready
Autonomic neuropathy v0.11 DST Alison Yeung Added comment: Comment when marking as ready: Single family reported 2012
Autonomic neuropathy v0.11 DST Alison Yeung Gene: dst has been classified as Red List (Low Evidence).
Autonomic neuropathy v0.11 DST Alison Yeung Classified gene: DST as Red List (low evidence)
Autonomic neuropathy v0.11 DST Alison Yeung Gene: dst has been classified as Red List (Low Evidence).
Autonomic neuropathy v0.10 DST Alison Yeung gene: DST was added
gene: DST was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: DST was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: DST were set to OMIM# 614653 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VI; HSAN6
Review for gene: DST was set to AMBER
gene: DST was marked as current diagnostic
Added comment: single consanguineous family reported
Sources: Literature
Autonomic neuropathy v0.9 RETREG1 Alison Yeung Marked gene: RETREG1 as ready
Autonomic neuropathy v0.9 RETREG1 Alison Yeung Gene: retreg1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.9 RETREG1 Alison Yeung Classified gene: RETREG1 as Green List (high evidence)
Autonomic neuropathy v0.9 RETREG1 Alison Yeung Gene: retreg1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.8 RETREG1 Alison Yeung gene: RETREG1 was added
gene: RETREG1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: RETREG1 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: RETREG1 were set to OMIM# 613115 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE IIB; HSAN2B
Review for gene: RETREG1 was set to GREEN
gene: RETREG1 was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.7 SCN11A Alison Yeung Classified gene: SCN11A as Green List (high evidence)
Autonomic neuropathy v0.7 SCN11A Alison Yeung Gene: scn11a has been classified as Green List (High Evidence).
Autonomic neuropathy v0.6 SCN11A Alison Yeung Marked gene: SCN11A as ready
Autonomic neuropathy v0.6 SCN11A Alison Yeung Gene: scn11a has been classified as Red List (Low Evidence).
Autonomic neuropathy v0.6 SCN11A Alison Yeung gene: SCN11A was added
gene: SCN11A was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: SCN11A was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes for gene: SCN11A were set to OMIM# 615548 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE VII; HSAN7
Review for gene: SCN11A was set to GREEN
gene: SCN11A was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.5 NTRK1 Alison Yeung Marked gene: NTRK1 as ready
Autonomic neuropathy v0.5 NTRK1 Alison Yeung Gene: ntrk1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.5 NTRK1 Alison Yeung Classified gene: NTRK1 as Green List (high evidence)
Autonomic neuropathy v0.5 NTRK1 Alison Yeung Gene: ntrk1 has been classified as Green List (High Evidence).
Autonomic neuropathy v0.4 NTRK1 Alison Yeung gene: NTRK1 was added
gene: NTRK1 was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: NTRK1 was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: NTRK1 were set to OMIM# 191315 NEUROTROPHIC TYROSINE KINASE, RECEPTOR, TYPE 1; NTRK1
Review for gene: NTRK1 was set to GREEN
Added comment: Sources: Literature
Autonomic neuropathy v0.3 NGF Alison Yeung Classified gene: NGF as Green List (high evidence)
Autonomic neuropathy v0.3 NGF Alison Yeung Gene: ngf has been classified as Green List (High Evidence).
Autonomic neuropathy v0.2 NGF Alison Yeung gene: NGF was added
gene: NGF was added to Autonomic neuropathy. Sources: Literature
Mode of inheritance for gene: NGF was set to BIALLELIC, autosomal or pseudoautosomal
Phenotypes for gene: NGF were set to OMIM #608654 NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE V; HSAN5
Review for gene: NGF was set to GREEN
gene: NGF was marked as current diagnostic
Added comment: Sources: Literature
Autonomic neuropathy v0.1 Alison Yeung Panel status changed from internal to public
Autonomic neuropathy v0.0 Alison Yeung Added Panel Autonomic neuropathy
Set panel types to: Victorian Clinical Genetics Services; Rare Disease