PanelApp
  1. Genes and Genomic Entities
  2. DNMT1

DNMT1

DNA methyltransferase 1
OMIM: 126375, Gene2Phenotype

6 panels

Panel Reviews Mode of inheritance Details
6 panels

Green DNMT1 in Early-onset Dementia


Level 2: Neurology and neurodevelopmental disorders
Version 1.50

Component of the following Super Panels:

  • Neurodegenerative disease - adult onset
  • Progressive Neurological Conditions

    		•  1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • ClinGen
    • Expert Review Green
    Phenotypes
    • Hereditary sensory neuropathy-deafness-dementia syndrome, MONDO:0013584

    Green DNMT1 in Mendeliome


    Version 1.3512

    		3 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Literature
    • ClinGen
    • Expert Review Green
    Phenotypes
    • Hereditary sensory neuropathy-deafness-dementia syndrome, MONDO:0013584

    Green DNMT1 in Regression


    Level 2: Neurology and neurodevelopmental disorders
    Version 0.594

    		0 reviews Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green DNMT1 in Deafness_IsolatedAndComplex


    Level 2: Hearing and ear disorders
    Version 1.238

    		1 review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Literature
    • ClinGen
    • Expert Review Green
    Phenotypes
    • Hereditary sensory neuropathy-deafness-dementia syndrome, MONDO:0013584

    Green DNMT1 in Ataxia - adult onset


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.59

    Component of the following Super Panels:

  • Ataxia_Superpanel
  • Neurodegenerative disease - adult onset
  • Neuromuscular Superpanel
  • Progressive Neurological Conditions

    		•  3 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Literature
    • ClinGen
    • Expert Review Green
    Phenotypes
    • Hereditary sensory neuropathy-deafness-dementia syndrome, MONDO:0013584

    Green DNMT1 in Hereditary Neuropathy_CMT - isolated


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.68

    Component of the following Super Panels:

  • Hereditary Neuropathy_CMT_IsolatedAndComplex
  • Neuromuscular Superpanel
  • Progressive Neurological Conditions

    		•  3 reviews MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
    Sources
    • Literature
    • ClinGen
    • Expert Review Green
    Phenotypes
    • Hereditary sensory neuropathy-deafness-dementia syndrome, MONDO:0013584