PanelApp
  1. Genes and Genomic Entities
  2. RAD51C

RAD51C

RAD51 paralog C
OMIM: 602774, Gene2Phenotype

10 panels

Panel Reviews Mode of inheritance Details
10 panels

Green RAD51C in Bone Marrow Failure


Level 2: Haematological disorders
Version 1.114

Component of the following Super Panels:

  • Immunological disorders_SuperPanel

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in Chromosome Breakage Disorders


    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 1.21

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in Mendeliome


    Version 1.2374

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anaemia, complementation group O (MIM#613390)

    Red RAD51C in Cancer Predisposition_Paediatric


    Level 2: Cancer
    Version 0.131

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in Radial Ray Abnormalities


    Level 2: Dysmorphic and congenital abnormality syndromes
    Version 1.15

    Component of the following Super Panels:

  • Limb and Digital Malformations SuperPanel

    		•  review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in Growth failure


    Version 1.76

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert Review
    Phenotypes
    • Fanconi anaemia, complementation group O, MIM# 613390

    Green RAD51C in Fetal anomalies


    Version 1.314

    		review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in IBMDx study


    Version 0.35

    		review Unknown
    Sources
    • Expert Review Green
    • IBMDx Study
    • Expert Review Green
    • Victorian Clinical Genetics Services
    Phenotypes
    • Fanconi anemia, complementation group O, MIM# 613390

    Green RAD51C in Ovarian Cancer


    Level 2: Cancer Predisposition
    Version 1.1

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Ovarian cancer, MONDO:0008170
    • RAD51C-related cancer predisposition, MONDO:0700273
    • Breast-ovarian cancer, familial, susceptibility to, 3, MONDO:0013253
    • Breast-ovarian cancer, familial, susceptibility to, 3, MIM#613399

    Green RAD51C in Breast Cancer


    Level 2: Cancer Predisposition
    Version 1.1

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Expert Review
    • Expert list
    Phenotypes
    • Breast cancer, MONDO:0007254
    • RAD51C-related cancer predisposition, MONDO:0700273
    • Breast-ovarian cancer, familial, susceptibility to, 3, MONDO:0013253
    • Breast-ovarian cancer, familial, susceptibility to, 3, MIM#613399