TLR7

toll like receptor 7
OMIM: 300365, Gene2Phenotype

4 panels

Panel Reviews Mode of inheritance Details
4 panels

Green TLR7 in Mendeliome


Version 1.2374

review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Immunodeficiency 74, COVID19-related, X-linked, MIM# 301051
  • Systemic lupus erythematosus 17, MIM# 301080

Green TLR7 in Disorders of immune dysregulation


Level 2: Immunological disorders
Version 1.10

Component of the following Super Panels:

  • Immunological disorders_SuperPanel
  • review X-LINKED: hemizygous mutation in males, monoallelic mutations in females may cause disease (may be less severe, later onset than males)
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Systemic lupus erythematosus 17, MIM# 301080

    Green TLR7 in Defects of intrinsic and innate immunity


    Level 2: Immunological disorders
    Version 1.20

    Component of the following Super Panels:

  • Immunological disorders_SuperPanel
  • review X-LINKED: hemizygous mutation in males, biallelic mutations in females
    Sources
    • Expert Review Green
    • Expert list
    • Expert Review Green
    • Expert list
    Phenotypes
    • Immunodeficiency 74, COVID-19-related, X-linked MONDO:0026767

    Green TLR7 in Susceptibility to Viral Infections


    Level 2: Immunological disorders
    Version 0.131

    Component of the following Super Panels:

  • Immunological disorders_SuperPanel
  • review X-LINKED: hemizygous mutation in males, biallelic mutations in females
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Immunodeficiency 74, COVID19-related, X-linked, MIM# 301051