WARS

tryptophanyl-tRNA synthetase
OMIM: 191050, ClinGen, DECIPHER

5 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 5 panels
Green WARS in Mendeliome Version 1.4541	3 reviews	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Green Expert Review Green Literature Phenotypes Neuronopathy, distal hereditary motor, type IX (OMIM:617721) juvenile to adult onset (15-23 years) Neurodevelopmental disorder withmicrocephaly and speech delay, with or without brain abnormalities, MIM# 620317
Green WARS in Microcephaly Level 2: Dysmorphic and congenital abnormality syndromes Version 1.418	2 reviews	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Neurodevelopmental disorder withmicrocephaly and speech delay, with or without brain abnormalities,MIM# 620317
Green WARS in Intellectual disability syndromic and non-syndromic Level 2: Neurology and neurodevelopmental disorders Version 1.699	2 reviews	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Neurodevelopmental disorder withmicrocephaly and speech delay, with or without brain abnormalities,MIM# 620317
Green WARS in Leukodystrophy Level 2: Neurology and neurodevelopmental disorders Version 0.392 Component of the following Super Panels: Progressive Neurological Conditions	2 reviews	BIALLELIC, autosomal or pseudoautosomal	Sources Expert Review Green Literature Phenotypes Neurodevelopmental disorder withmicrocephaly and speech delay, with or without brain abnormalities,MIM# 620317
Amber WARS in Hereditary Neuropathy Level 2: Neurology and neurodevelopmental disorders Version 1.186 Component of the following Super Panels: Neuromuscular Superpanel Progressive Neurological Conditions	3 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Royal Melbourne Hospital Literature Expert Review Amber Expert Review Amber Literature Phenotypes Neuronopathy, distal hereditary motor, type IX, MIM#617721