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Clefting disorders v1.130 GRHL2 Zornitza Stark Marked gene: GRHL2 as ready
Clefting disorders v1.130 GRHL2 Zornitza Stark Gene: grhl2 has been classified as Amber List (Moderate Evidence).
Clefting disorders v1.130 GRHL2 Zornitza Stark Classified gene: GRHL2 as Amber List (moderate evidence)
Clefting disorders v1.130 GRHL2 Zornitza Stark Gene: grhl2 has been classified as Amber List (Moderate Evidence).
Clefting disorders v1.129 GRHL2 Zornitza Stark gene: GRHL2 was added
gene: GRHL2 was added to Clefting disorders. Sources: Literature
Mode of inheritance for gene: GRHL2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Publications for gene: GRHL2 were set to 41172132
Disease associations for gene: GRHL2 were set to Orofacial cleft, MONDO:0000358, GRHL2-related
Review for gene: GRHL2 was set to AMBER
Added comment: PMID 41172132 enrichment of GRHL2 variants in a cohort of individuals with orofacial clefts, identifying 2 individuals with de novo high impact variants. Two further individuals identified in other cohorts/via Gene Matcher with structural variants.
Sources: Literature