SCN5A

sodium voltage-gated channel alpha subunit 5
OMIM: 600163, Gene2Phenotype

17 panels

Panel	Reviews	Mode of inheritance	Details
Filter panels 17 panels
Green SCN5A in Brugada syndrome Level 2: Cardiovascular disorders Version 0.34 Component of the following Super Panels: Adult Cardiac SuperPanel Arrhythmia_SuperPanel	2 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Atrial fibrillation, familial, 10 Brugada syndrome 1 Cardiomyopathy, dilated, 1E Heart block, nonprogressive Heart block, progressive, type IA Long QT syndrome 3 Sick sinus syndrome 1 Ventricular fibrillation, familial, 1 {Sudden infant death syndrome, susceptibility to}
Green SCN5A in Dilated Cardiomyopathy Level 2: Cardiovascular disorders Version 1.48 Component of the following Super Panels: Adult Cardiac SuperPanel Cardiomyopathy_Adult_SuperPanel	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Cardiomyopathy, dilated, 1E, MIM# 601154
Green SCN5A in Hydrops fetalis Level 2: Dysmorphic and congenital abnormality syndromes Version 0.328	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Expert Review Phenotypes Long QT syndrome 3 (MIM#603830)
Green SCN5A in Incidentalome Version 0.360	3 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Victorian Clinical Genetics Services Phenotypes Long QT syndrome 3 (MIM#603830) Sick sinus syndrome 1, MIM# 608567 Ventricular fibrillation, familial, 1, MIM# 603829 Brugada syndrome 1, MIM# 601144 Heart block, progressive, type IA, MIM# 113900 Cardiomyopathy, dilated, 1E, MIM# 601154 Tags cardiac
Green SCN5A in Long QT Syndrome Level 2: Cardiovascular disorders Version 0.61 Component of the following Super Panels: Adult Cardiac SuperPanel Arrhythmia_SuperPanel	2 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Long QT syndrome 3 (MIM#603830)
Red SCN5A in Short QT syndrome Level 2: Cardiovascular disorders Version 1.7 Component of the following Super Panels: Adult Cardiac SuperPanel Arrhythmia_SuperPanel	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Red Expert Review Phenotypes Short QT syndrome Tags disputed
Green SCN5A in Ventricular Fibrillation Level 2: Cardiovascular disorders Version 0.5 Component of the following Super Panels: Adult Cardiac SuperPanel Arrhythmia_SuperPanel	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Ventricular fibrillation, familial, 1, MIM# 603829
Green SCN5A in Additional findings_Adult Level 2: Screening Version 1.130	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Melbourne Genomics Health Alliance Phenotypes Atrial fibrillation, familial, 10, MIM# 614022 Brugada syndrome 1, MIM# 601144 AD 3 Cardiomyopathy, dilated, 1E 601154 AD 3 Heart block, nonprogressive, MIM# 113900 Heart block, progressive, type IA, MIM# 113900 Long QT syndrome 3, MIM# 603830
Green SCN5A in Stroke Level 2: Neurology and neurodevelopmental disorders Version 1.28	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Literature Phenotypes Atrial fibrillation, familial, 10 MIM#614022
Green SCN5A in Cardiomyopathy_Paediatric Level 2: Cardiovascular disorders Version 0.207	0 reviews	MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown	Sources Expert Review Green South West GLH NHS GMS Phenotypes Dilated cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Brugada syndrome Cardiomyopathy, dilated, 1E Long QT syndrome
Amber SCN5A in Additional findings_Paediatric Level 2: Screening Version 0.278	0 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber BabySeq Category B gene Phenotypes Brugada syndrome Long QT syndrome
Amber SCN5A in Incidentalome_PREGEN_DRAFT Version 0.43	1 review	Unknown	Sources Expert Review Amber NSW Health Pathology
Green SCN5A in Fetal anomalies Version 1.465	2 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Literature Expert list Expert Review Green Expert Review Phenotypes Sudden infant death syndrome, susceptibility to - #272120 Long QT syndrome 3 - #603830
Amber SCN5A in Genomic newborn screening: BabyScreen+ Level 2: Screening Version 1.140	1 review	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Amber BabySeq Category B gene BeginNGS Phenotypes Long QT syndrome 3 (MIM#603830) Brugada syndrome 1, MIM# 601144 Tags cardiac treatable
Green SCN5A in Transplant Co-Morbidity Level 2: Screening Version 0.20	0 reviews	MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted	Sources Expert Review Green Victorian Clinical Genetics Services Phenotypes Heart block, nonprogressive Atrial fibrillation, familial, 10 Long QT syndrome 3 Ventricular fibrillation, familial, 1 Cardiomyopathy, dilated, 1E, MIM# 601154 Sick sinus syndrome 1 Heart block, progressive, type IA Brugada syndrome 1 {Sudden infant death syndrome, susceptibility to}
Green SCN5A in Cardiac conduction disease Level 2: Cardiovascular disorders Version 1.3 Component of the following Super Panels: Adult Cardiac SuperPanel Arrhythmia_SuperPanel	2 reviews	BOTH monoallelic and biallelic (but BIALLELIC mutations cause a more SEVERE disease form), autosomal or pseudoautosomal	Sources Expert Review Green NHS GMS Expert Review Green Victorian Clinical Genetics Services Phenotypes progressive familial heart block MONDO:0019490
Red SCN5A in Infertility and Recurrent Pregnancy Loss Version 1.50	2 reviews	BOTH monoallelic and biallelic, autosomal or pseudoautosomal	Sources Expert Review Red Literature