PanelApp
  1. Genes and Genomic Entities
  2. WDR4

WDR4

WDR4 tRNA N7-guanosine methyltransferase non-catalytic subunit
OMIM: 605924, ClinGen, DECIPHER

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green WDR4 in Mendeliome


Version 2.577

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Galloway-Mowat syndrome 6, OMIM #618347
  • Microcephaly, growth deficiency, seizures, and brain malformations, OMIM #618346

Green WDR4 in Microcephaly


Level 2: Dysmorphic and congenital abnormality syndromes
Version 2.32

2 reviews BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Expert Review Green
  • Victorian Clinical Genetics Services
  • Victorian Clinical Genetics Services
Phenotypes
  • Galloway-Mowat syndrome 6 MIM#618347
  • Microcephaly, growth deficiency, seizures, and brain malformations, OMIM #618346

Green WDR4 in Proteinuria


Level 2: Renal and urinary tract disorders
Version 1.3

Component of the following Super Panels:

  • Kidneyome_SuperPanel
  • Renal Glomerular Disease_SuperPanel

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Galloway-Mowat syndrome 6, OMIM #618347

    Green WDR4 in Callosome


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.25

    		1 review Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green WDR4 in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 2.145

    		2 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    Phenotypes
    • Galloway-Mowat syndrome 6, OMIM #618347
    • Microcephaly, growth deficiency, seizures, and brain malformations, OMIM #618346

    Green WDR4 in Skeletal dysplasia

    Level 3: Skeletal dysplasias
    Level 2: Skeletal disorders
    Version 1.151

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Microcephaly, growth deficiency, seizures, and brain malformations, MONDO:0032690

    Green WDR4 in Fetal anomalies


    Version 2.81

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Microcephaly, growth deficiency, seizures, and brain malformations, OMIM # 618346