PanelApp
  1. Genes and Genomic Entities
  2. ZFHX3

ZFHX3

zinc finger homeobox 3
OMIM: 104155, Gene2Phenotype

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green ZFHX3 in Mendeliome


Version 1.3512

3 reviews BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Neurodevelopmental disorder, MONDO:0700092, ZFHX3-related
  • developmental and epileptic encephalopathy MONDO:0100062, ZFHX3-related

Green ZFHX3 in Genetic Epilepsy


Level 2: Neurology and neurodevelopmental disorders
Version 1.267

Component of the following Super Panels:

  • Progressive Neurological Conditions

    		•  1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • developmental and epileptic encephalopathy MONDO:0100062

    Green ZFHX3 in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.410

    		2 reviews MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Research
    Phenotypes
    • Neurodevelopmental disorder, MONDO:0700092, ZFHX3-related

    Green ZFHX3_SCA4_GGC STR in Mendeliome


    Version 1.3512

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • spinocerebellar ataxia type 4 MONDO:0010847

    Green ZFHX3_SCA4_GGC STR in Ataxia - adult onset


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.59

    Component of the following Super Panels:

  • Ataxia_Superpanel
  • Neurodegenerative disease - adult onset
  • Neuromuscular Superpanel
  • Progressive Neurological Conditions

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • spinocerebellar ataxia type 4 MONDO:0010847

    Green ZFHX3_SCA4_GGC STR in Hereditary Neuropathy - complex


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.40

    Component of the following Super Panels:

  • Hereditary Neuropathy_CMT_IsolatedAndComplex
  • Neuromuscular Superpanel
  • Progressive Neurological Conditions

    		•  review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • spinocerebellar ataxia type 4 MONDO:0010847

    Green ZFHX3_SCA4_GGC STR in Repeat Disorders


    Version 0.269

    		review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • spinocerebellar ataxia type 4 MONDO:0010847