PanelApp
  1. Genes and Genomic Entities
  2. MEGF10

MEGF10

multiple EGF like domains 10
OMIM: 612453, ClinGen, DECIPHER

7 panels

Panel Reviews Mode of inheritance Details
7 panels

Green MEGF10 in Mendeliome


Version 1.3795

1 review BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • Victorian Clinical Genetics Services
Phenotypes
  • Myopathy, areflexia, respiratory distress, and dysphagia, early-onset, MIM# 614399

Green MEGF10 in Muscular dystrophy and myopathy_Paediatric


Level 2: Neurology and neurodevelopmental disorders
Version 1.112

Component of the following Super Panels:

  • Myopathy Superpanel
  • Neuromuscular Superpanel

    		•  2 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Expert list
    • Expert Review Green
    Phenotypes
    • MEGF10-Related Myopathy MONDO:0013731

    Green MEGF10 in Mackenzie's Mission_Reproductive Carrier Screening


    Level 2: Screening
    Version 0.111

    		0 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Mackenzie's Mission
    Phenotypes
    • Myopathy, areflexia, respiratory distress, and dysphagia, early-onset, 614399 (3)

    Green MEGF10 in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    		0 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • BabySeq Category A gene
    • Expert Review Green
    Phenotypes
    • Myopathy, areflexia, respiratory distress, and dysphagia, early-onset

    Green MEGF10 in Fetal anomalies


    Version 1.481

    		2 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genomics England PanelApp
    Phenotypes
    • Myopathy, areflexia, respiratory distress, and dysphagia, early-onset (MIM#614399)

    Green MEGF10 in Prepair 1000+


    Level 2: Screening
    Version 2.15

    		1 review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Mackenzie's Mission
    Phenotypes
    • Congenital myopathy 10A, severe variant, MIM #614399
    • Congenital myopathy 10B, mild variant, MIM #620249

    Red MEGF10 in Genomic newborn screening: BabyScreen+


    Level 2: Screening
    Version 1.141

    		2 reviews BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • BabySeq Category A gene
    Phenotypes
    • Myopathy, areflexia, respiratory distress, and dysphagia, early-onset, MIM# 614399