SCN1B

sodium voltage-gated channel beta subunit 1
OMIM: 600235, Gene2Phenotype

9 panels

Panel Reviews Mode of inheritance Details
9 panels

Red SCN1B in Brugada syndrome


Level 2: Cardiovascular disorders
Version 0.34

Component of the following Super Panels:

  • Adult Cardiac SuperPanel
  • Arrhythmia_SuperPanel
  • review Unknown
    Sources
    • Expert Review Red
    • Victorian Clinical Genetics Services
    Tags
    • disputed

    Green SCN1B in Incidentalome


    Version 0.316

    review Unknown
    Sources
    • Victorian Clinical Genetics Services
    • Expert Review Green

    Green SCN1B in Genetic Epilepsy


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.145

    Component of the following Super Panels:

  • Progressive Neurological Conditions
  • review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Victorian Clinical Genetics Services
    • Australian Genomics Health Alliance Epilepsy Flagship
    Phenotypes
    • Developmental and epileptic encephalopathy (MONDO:0100062)
    • generalized epilepsy with febrile seizures plus (MONDO:0018214)

    Green SCN1B in Intellectual disability syndromic and non-syndromic


    Level 2: Neurology and neurodevelopmental disorders
    Version 1.118

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Genetic Health Queensland
    Phenotypes
    • Epileptic encephalopathy, early infantile, 52, MIM#617350

    Red SCN1B in Additional findings_Paediatric


    Level 2: Screening
    Version 0.278

    review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Red
    • BabySeq Category C gene
    Phenotypes
    • Brugada syndrome

    Red SCN1B in Fetal anomalies


    Version 1.321

    review BOTH monoallelic and biallelic, autosomal or pseudoautosomal
    Sources
    • Expert Review Red
    • Genomics England PanelApp
    • Genetic Health Queensland
    Phenotypes
    • Epileptic encephalopathy, early infantile, 52, MIM#617350
    • Atrial fibrillation, familial, 13, MIM# 615377

    Green SCN1B in Prepair 1000+


    Level 2: Screening
    Version 2.7

    review BIALLELIC, autosomal or pseudoautosomal
    Sources
    • Expert Review Green
    • Literature
    Phenotypes
    • Developmental and epileptic encephalopathy 52, MIM#617350

    Red SCN1B in Genomic newborn screening: BabyScreen+


    Level 2: Screening
    Version 1.117

    review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • BabySeq Category C gene
    • Expert Review Red
    Phenotypes
    • Brugada syndrome

    Amber SCN1B in Cardiac conduction disease


    Level 2: Cardiovascular disorders
    Version 1.0

    Component of the following Super Panels:

  • Adult Cardiac SuperPanel
  • Arrhythmia_SuperPanel
  • review MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
    Sources
    • Expert Review Amber
    • NHS GMS
    Phenotypes
    • Heart conduction disease MONDO:0000992