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Mendeliome

Gene: DRD3

Red List (low evidence)

DRD3 (dopamine receptor D3)
EnsemblGeneIds (GRCh38): ENSG00000151577
EnsemblGeneIds (GRCh37): ENSG00000151577
OMIM: 126451, Gene2Phenotype
DRD3 is in 1 panel

1 review

Krithika Murali (Victorian Clinical Genetics Services)

Red List (low evidence)

Currently reported to be a schizophrenia or essential tremor susceptibility gene.
Created: 14 May 2022, 12:18 p.m. | Last Modified: 14 May 2022, 12:18 p.m.
Panel Version: 0.14291

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Phenotypes
{Essential tremor, hereditary, 1} - MIM#190300; {Schizophrenia, susceptibility to} - MIM#181500

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Sources
  • Expert Review Red
  • Victorian Clinical Genetics Services
Phenotypes
  • {Essential tremor, hereditary, 1} - MIM#190300
  • {Schizophrenia, susceptibility to} - MIM#181500
OMIM
126451
Clinvar variants
Variants in DRD3
Penetrance
None
Publications
Panels with this gene

History Filter Activity

28 Feb 2025, Gel status: 1

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: DRD3 were set to 16650084; 16809426; 17339592

28 Feb 2025, Gel status: 1

Set publications

Bryony Thompson (Royal Melbourne Hospital)

Publications for gene: DRD3 were set to

20 May 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: drd3 has been classified as Red List (Low Evidence).

20 May 2022, Gel status: 1

Set Phenotypes

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Phenotypes for gene: DRD3 were changed from to {Essential tremor, hereditary, 1} - MIM#190300; {Schizophrenia, susceptibility to} - MIM#181500

20 May 2022, Gel status: 1

Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Mode of inheritance for gene: DRD3 was changed from Unknown to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

20 May 2022, Gel status: 1

Entity classified by Genomics England curator

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

Gene: drd3 has been classified as Red List (Low Evidence).

17 Nov 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance

Zornitza Stark (Victorian Clinical Genetics Services; Australian Genomics)

gene: DRD3 was added gene: DRD3 was added to Mendeliome_VCGS. Sources: Expert Review Green,Victorian Clinical Genetics Services Mode of inheritance for gene: DRD3 was set to Unknown